Stabilization of a new antiulcer drug (Lansoprazole) in the solid dosage forms
- 1 January 1992
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 18 (13) , 1437-1447
- https://doi.org/10.3109/03639049209040850
Abstract
In the previous study, we clarified that enteric granules were appropriate dosage forms of lansoprazole. The establishment of these formulations, however, was difficult because some of the excipients needed for these formulations are incompatible with the drug. We examined the effects of adding magnesium carbonate as an alkaline stabilizer and could get stable enteric granules. We also discuss the mechanism of stabilization.Keywords
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