Some Histochemical Observations on the Human Aortic Wall in Atherosclerosis
- 1 November 1960
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 8 (6) , 1274-1277
- https://doi.org/10.1161/01.res.8.6.1274
Abstract
A decrease in the ATPase (heat stable) and 5-nucleotidase of atherosclerotic regions in human aortae has been demonstrated. An increase in the breakdown of TPN, as measured by phosphate release, of the atherosclerotic aorta as a whole has been shown. No change was observed in the breakdown of DPN, as measured by phosphate release, between the normal or atherosclerotic aorta. No reactivity for glucose-1 or glucose-6-phosphate or β-glycerophosphate was found in the intima or media. The possible implications in the development of atheroma are discussed.Keywords
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- Adenosine Triphosphatase Activity of the Vascular System.Experimental Biology and Medicine, 1952