Microbial Structures in a Patient With Sporadic Non‐A, Non‐B Fulminant Hepatitis Treated by Liver Transplantation

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Abstract
Double‐shelled virus‐like panicles (60 nm) and long cytoplasmic tubular structures were found in the cytoplasmic of hepatocytes from areas of collapsed and regenerating areas of hepatectomised liver in a 13‐year‐old boy who received a liver graft for fulminant hepatitis attributed to sporadic non‐A, non‐B hepatitis. The patient died on the ninth postoprative day from acute graft failure. Although virus‐like particles were not found. instead, gram‐negative rods were identified in the necrotic graft and the most likely cause of death was a gram‐negative septicaemia with a Shwartzman‐like reaction localized to the liver.