Ramycin: A New Antibiotic
- 1 April 1958
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 18 (2) , 377-381
- https://doi.org/10.1099/00221287-18-2-377
Abstract
A strain of Mucor ramannianus from Campine forest soil was found to secrete an antibiotic, for which the name ramycin is proposed. It is especially active against Gram-positive micro-organisms and Mycobacterium tuberculosis H37Rv, but sensitive organisms quickly acquire resistance to it. Although it is not very toxic, it possesses a necrotic action on tissues. Ramycin can protect mice against strepto-coccal and staphylococcal infections but not against H37Rv. Ramycin crystallizes in orthorhombic plates. The new antibiotic is an optically-inactive unsaturated hydroxy acid, containing C, H and O only.Keywords
This publication has 0 references indexed in Scilit: