Reed-Sternberg/lymphocyte rosette: lymphocyte subpopulations as defined by monoclonal antibodies.
Open Access
- 1 July 1984
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 37 (7) , 767-771
- https://doi.org/10.1136/jcp.37.7.767
Abstract
The Reed-Sternberg cell/lymphocyte rosette characteristic of Hodgkin's disease tissue and cell suspensions was investigated with monoclonal antibodies on fresh viable cell suspensions prepared from nine cases of Hodgkin's disease. The biopsy material comprised six spleens and three lymph nodes. The majority of the rosetting lymphocytes were T cells, primarily of the helper subset. Some of the attached lymphocytes were suppressor T cells. In addition, a few of the rosetting lymphocytes around Reed-Sternberg cells were B cells.This publication has 29 references indexed in Scilit:
- The reactivity of Reed–Sternberg cells with monoclonal antisera at thin section and ultrastructural levelsThe Journal of Pathology, 1983
- The reaction of xenogeneic and monoclonal antisera with Reed-Sternberg cellsThe Journal of Pathology, 1982
- Human T lymphocyte subpopulations defined by Fc receptors and monoclonal antibodies. A comparison.The Journal of Experimental Medicine, 1980
- Monoclonal Antibodies Defining Distinctive Human T Cell Surface AntigensScience, 1979
- Hodgkin's disease with lymphocytic predominance, nodular type (nodular paragranuloma) and progressively transformed germinal centres—a cytohistological studyHistopathology, 1979
- Properties of Anti-Hairy Cell SerumBritish Journal of Haematology, 1979
- DENDRITIC CELLS AND B LYMPHOCYTES IN HODGKIN'S DISEASEThe Lancet, 1977
- Rosetting and other reactions of the Reed‐Sternberg cellThe Journal of Pathology, 1977
- SURFACE CHARACTERISTICS OF HODGKIN'S LYMPHOMA CELLSThe Lancet, 1974
- ORIGIN OF HODGKIN'S CELLThe Lancet, 1974