Does nicotine influence cytokine profile and subsequent cell cycling/apoptotic responses in inflammatory bowel disease?
- 1 November 2008
- journal article
- research article
- Published by Oxford University Press (OUP) in Inflammatory Bowel Diseases
- Vol. 14 (11) , 1469-1482
- https://doi.org/10.1002/ibd.20523
Abstract
Background. Smoking differentially influences susceptibility to the inflammatory bowel diseases (IBDs) Crohn's disease (CD) and ulcerative colitis (UC). We invKeywords
This publication has 69 references indexed in Scilit:
- Chronic nicotine stimulation modulates the immune response of mucosal T cells to Th1-dominant pattern via nAChR by upregulation of Th1-specific transcriptional factorNeuroscience Letters, 2008
- Unravelling the pathogenesis of inflammatory bowel diseaseNature, 2007
- The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune diseaseClinical and Experimental Immunology, 2007
- Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-κB phosphorylation and nuclear factor-κB transcriptional activity through nicotinic acetylcholine receptor α7Clinical and Experimental Immunology, 2006
- IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6Journal of Clinical Investigation, 2006
- α7 Nicotinic Acetylcholine Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 and -12 Production in MonocytesJournal of Pharmacological Sciences, 2006
- Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1–dependent pathwayThe Journal of Experimental Medicine, 2005
- Inflammatory Bowel Disease and SmokingInflammatory Bowel Diseases, 2004
- Nicotine increases oxidative stress, activates NF-κB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesisChemico-Biological Interactions, 2003
- Transdermal Nicotine for Active Ulcerative ColitisNew England Journal of Medicine, 1994