E: A Third Hepatitis B Antigen?
- 1 April 1976
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 294 (14) , 779-781
- https://doi.org/10.1056/nejm197604012941411
Abstract
Since the discovery of the Australia antigen and its specific association with Type B hepatitis, the factors involved in the immune response to this viral infection have become increasingly complex. The complete hepatitis B virus (HBV) is now believed to be the 43-nm "Dane" particle, composed of a 27-nm core (hepatitis B core antigen, HBc Ag) and a 7-nm to 8-nm antigenically distinct coat (hepatitis B surface antigen, HBs Ag). HBs Ag reactivity also characterizes the much more numerous 22-nm-diameter spherical and tubular particles, which appear to represent excess virus coat material released from HBV-infected liver cells. . . .Keywords
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