Privileged scaffolds for library design and drug discovery
Top Cited Papers
- 18 March 2010
- journal article
- review article
- Published by Elsevier in Current Opinion in Chemical Biology
- Vol. 14 (3) , 347-361
- https://doi.org/10.1016/j.cbpa.2010.02.018
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Combinatorial Library Synthesis and Biological Evaluation of Pyrazolo[4,3‐e][1,4]diazepine as a Potential Privileged StructureChemMedChem, 2009
- Discovery of Indoline-Based, Natural-Product-like Compounds as Probes of Focal Adhesion Kinase Signaling PathwaysJournal of Combinatorial Chemistry, 2009
- Chemical Proteomics-Based Drug Design: Target and Antitarget Fishing with a Catechol−Rhodanine Privileged Scaffold for NAD(P)(H) Binding ProteinsJournal of Medicinal Chemistry, 2008
- Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolonesJournal of Medicinal Chemistry, 2008
- Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound librariesNatural Product Reports, 2008
- Towards the Optimal Screening Collection: A Synthesis StrategyAngewandte Chemie International Edition in English, 2007
- The principle of complementarity: chemical versus biological spaceCurrent Opinion in Chemical Biology, 2005
- The evolving role of natural products in drug discoveryNature Reviews Drug Discovery, 2005
- Exploring biology with small organic moleculesNature, 2004
- Lasercodierung in der kombinatorischen ChemieAngewandte Chemie, 1997