Adrenergic nerves and the alpha2‐adrenoceptor system regulating melanosome aggregation within fish melanophores
- 1 June 1984
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 121 (2) , 173-179
- https://doi.org/10.1111/j.1748-1716.1984.tb07444.x
Abstract
Nervous control of melanosome aggregation of melanophores of L. ossifagus was studied by electrical field stimulation of isolated scales. Field stimulation elicited a rapid melanosome aggregation which was reversible upon interruption of the stimuli. The response was blocked by guanethidine, indicating that adrenergic nerves were stimulated. The melanophore receptors which mediate the nerve-controlled pigment aggregation were characterized to be of the alpha2-adrenoceptor subtype, since they were inhibited by yohimbine but not by prazosin. Stimulation of the alpha2-adrenoceptors by noradrenaline [norepinephrine] was associated with a significant reduction of the cAMP content of the melanophores. Adrenergic nerves apparently control melanosome aggregation via alpha2-adrenoceptors and these receptors are coupled to the adenylate cyclase-cAMP system of the melanophores.Keywords
This publication has 14 references indexed in Scilit:
- Molecular mechanisms involved in α-adrenergic responsesTrends in Pharmacological Sciences, 1982
- Pharmacology of B‐HT 920 in some Isolated Smooth Muscles of the Guinea‐pigActa Pharmacologica et Toxicologica, 1982
- Action of melanophore-stimulating hormone on melanophores of the cyprinid fish Zacco temminckiComparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1982
- Pharmacological Evidence for Involvement of Presynaptic Alpha2 Adrenoceptors in Norepinephrinergic Neurotransmission Triggering the Release of Melanin-dispersing Hormone in the Fiddler Crab Uca PugilatorJournal of Crustacean Biology, 1982
- Microtubule treadmills—possible molecular machineryNature, 1981
- Molecular mechanisms involved in α-adrenergic responsesMolecular and Cellular Endocrinology, 1981
- Studies on the colour-change mechanism in a fresh-water teleost,Nandus nandus (Ham.) I. Neural controlJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1979
- Adrenergic Innervation and Drug Responses of the Oval Sphincter in the Swimbladder of the God (Gadus morhua)1Acta Physiologica Scandinavica, 1971
- Catecholamines in nerves and organs of Myxine glutinosa, Squalus acanthias, and Gadus callariasGeneral and Comparative Endocrinology, 1961
- The pigmentary effector system. VI. The dual character of endocrine co-ordination in amphibian colour changeProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1931