Conditions of Reactivation of Arthus-Type Inflammation by Thiol Compounds.

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Abstract
Summary Intradermal injection of GSH into healing sites of Arthus phenomenon produces a reactivation of the inflammatory process having the same aspect as the original reaction. The interval during which reactivation occurs is correlated with the susceptibility to GSH of a protease extracted from the healing sites, which decreases with the age of the lesion. Cysteine is less active in vivo than GSH but no difference was observed between the in vitro effects of the 2 thiol compounds.