Abstract
During a 21-yr period in Denmark 26 deaths were caused by wasp or bee stings (according to the National Health Service). The deaths might be classified, with some overlapping, as caused by either anaphylactic/anaphylactoid shocks (between 65 and 80%), suffocation after stings in the airways (about 15%) or preexisting diseases, especially arteriosclerotic heart disease (.apprx. 20%). Characteristically, in most persons with shock reactions unconsciousness and death occurred very shortly after the sting (within 45 min), while the interval between sting and death was longer (30 min to a couple of hours) when death was caused by suffocation. In > 21 of the 26 cases insect allergy might have contributed to the fatal outcome. Of these cases, 6 had a previous history of abnormal reactions to insect venom, thus only a small group would have benefited from the prophylactic effect of hyposensitization. There was no known previous history of reactions to insect stings in the other cases, but it is likely that > 6 persons had had severe reactions to insect stings on other occasions. Presumably many deaths where insect stings are involved, though not verified as causal, are classified as inexplicable or accidental, thus the real number of deaths caused by wasp or bee stings could be substantially greater. Consequently hyposensitization after severe insect sting reactions of verified allergic genesis can still be advised.

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