Antioestrogenic and antifertility compounds. I. 2-(NN-Dialkylamino)ethyl ethers of some stilbene-4,4'-diol and 4,4'-dihydroxybibenzyl derivatives
- 1 January 1967
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 20 (7) , 1413-1428
- https://doi.org/10.1071/ch9671413
Abstract
A series of α-methyl- and α,α?-dimethyl-stilbene and -bibenzyl compounds substituted in the 4,4?-positions with a hydroxyl (or methoxyl) group and a 2-(NN-dialkylamino)ethoxyl group has been synthesized to be tested for antioestrogenic and antifertility activity. The corresponding bis-2-(NN-dialkylamino)ethyl ethers are also described.Keywords
This publication has 8 references indexed in Scilit:
- THE OESTROGENIC AND ANTIFERTILITY ACTIVITIES OF DIETHYLSTILBOESTROL AND DIMETHYLSTILBOESTROL IN RODENTSActa Endocrinologica, 1965
- Mammalian Antifertility Agents. I. Derivatives of 2,3-Diphenylindenes1Journal of Medicinal Chemistry, 1965
- An Orally Effective Mammalian Antifertility AgentExperimental Biology and Medicine, 1962
- Gonadotrophin Inhibiting and Anti-Fecundity Effects of Chloramiphene.Experimental Biology and Medicine, 1960
- A NON-STEROIDAL ESTROGEN ANTAGONIST l-(p-2-DIETHYLAMINOETHOXYPHENYLH-PHENYL-2-p-METHOXYPHENYL ETHANOLEndocrinology, 1958
- An Orally Active Compound with Anti-Fertility Effects in Rats.Experimental Biology and Medicine, 1958
- Antispasmodics. III. Basic Alkyl Ester Acid Addition and Quaternary Ammonium Salts of α-(2-Cycloalken-1-yl)-2-thienylacetic AcidsJournal of the American Chemical Society, 1955
- LE TRAITEMENT DES ULCERES GASTRO-DUODENAUX PAR LE SERUM PRELEVE AU DECOURS DE LA CRISE ULCEREUSE1949