OBSERVATIONS ON THE COMBINED ACTION OF COLLOIDAL LEAD AND RADIATION ON TUMOURS
- 28 January 1928
- Vol. 1 (3499) , 132-133
- https://doi.org/10.1136/bmj.1.3499.132
Abstract
Mice inoculated with mouse tumor T/63 were used. When the tumor had grown to 5X5 mm., treatment was started. One group was radiated with 110 mgm. of RaBr2. 4 H2O in a 2X2 cm. applicator filtered through 0.15 mm. of Ag for 15 min. At intervals of 1, 2, 3, 4, 5 days thereafter 0.06 cc. of 0.5% colloidal Pb was injected into the tail vein. In another set the Pb was injected first and then radiation was given at intervals of 1, 2, 3, 4, 5, 7, 12 days afterwards. Controls were run with only Pb or radiation and showed little effect on the rate of growth. Best results were obtained when Pb was injected first, followed by radiation after 3 or 4 days. This treatment caused the tumor to disappear.This publication has 1 reference indexed in Scilit:
- A study of the direct and indirect action of X-rays upon the tissues of the embryonic fowlProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1927