The Inhibition of Ribo-and Thymo-Nucleic Acid Synthesis in Tumour Tissue by Irradiation with X rays

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Abstract
Using P32 as a tracer, the uptake of this element in the thymo-nucleic acid fraction in rat tumor tissue (Jensen rat sarcoma) is markedly inhibited by X-rays, while the ribo-nucleic acid fraction is inhibited to a smaller extent. Nembutal as a sedative inhibits the uptake of P32 in both these fractions and should not be used. There is confirmation of Hevesy''s observation that irradiation of one tumor can affect the nucleic acid metabolism of another tumor in the same animal.

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