Anticancer Activity and Protein Phosphatase 1 and 2A Inhibition of a New Generation of Cantharidin Analogues
- 1 February 2002
- journal article
- Published by Springer Nature in Investigational New Drugs
- Vol. 20 (1) , 1-11
- https://doi.org/10.1023/a:1014460818734
Abstract
Cantharidin (Spanish Fly) is a naturaltoxin and an inhibitor of proteinphosphatases 1 (PP1) and 2A (PP2A), whichhave key roles in cell cycle progression.We have synthesised two series ofdemethylated...Keywords
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