Cortical reorganisation in patients with MS

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Abstract
Over the past decade, modern structural magnetic resonance imaging (MRI) techniques have been extensively used for the study of patients with multiple sclerosis (MS).1 The ultimate goal of this research is to increase the understanding of the mechanisms responsible for the accumulation of irreversible disability. Although important insight into MS pathobiology has been achieved by using modern MR based techniques, the magnitude of the correlation between MRI and clinical findings remains suboptimal. This might be explained, at least partially, by the variable effectiveness of reparative and recovery mechanisms following MS related tissue damage.

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