Gaucher's disease in pregnancy associated with intra-uterine growth retardation

Abstract
Gaucher''s disease is an inborn error of intracellular metabolism, characterized by abnormal storage of cerebrosides in the reticuloendothelial cell A patient, 1st diagnosed as having Gaucher''s disease in pregnancy because she developed hemorrhagic complications and a progressive decrease in the fetal growth rate. Spontaneous improvement in the platelet count, which occurred from 33-38 wk, coincided with improved fetal growth. A possible association between Gaucher''s disease and its hemorrhagic complications, and intrauterine growth retardation is therefore suggested.

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