Serum dopamine‐β‐hydroxylase activity in clinical subtypes of depression
- 1 November 1989
- journal article
- research article
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 80 (5) , 474-478
- https://doi.org/10.1111/j.1600-0447.1989.tb03008.x
Abstract
Serum dopamine-.beta.-hydroxylase (DBH) activity was determined in male adult psychiatric patients (n = 280) and age-matched male healthy control (n = 100). Patients included in the study had no history of previous or current exposure to psychoactive drugs and were diagnosed according to Research Diagnostic Criteria. A significant decrease in serum DBH activity was noted in patients with psychotic major depressive disorder (n = 50) as compared with control. In acute schizophrenics (n = 100), nonpsychotic major depressives (n = 45) and patients with manic disorder (n = 85), mean DBH activity did not differ significantly from the control values.Keywords
This publication has 27 references indexed in Scilit:
- Studies on biogenic amine metabolizing enzymes (DBH, COMT, MAO) and pathogenesis of affective illness.Acta Psychiatrica Scandinavica, 1983
- Depression, antidepressants, and plasma DBHPsychiatry Research, 1981
- Serum DBH and Platelet MAO in Patients with Depressive DisordersPharmacopsychiatry, 1981
- Schizophrenia in a North Swedish geographical isolate, 1900–1977. Epidemiology, genetics and biochemistryClinical Genetics, 1978
- SERUM DOPAMINE‐β‐HYDROXYLASE IN SCHIZOPHRENIC PATIENTSJournal of Neurochemistry, 1978
- Studies on dopamine-β-hydroxylase in mental disordersJournal of Psychiatric Research, 1974
- Serum dopamine β-hydroxylase as an index of sympathetic functionLife Sciences, 1974
- Plasma Dopamine-β-Hydroxylase Activity in Hypertension and Various Neuropsychiatric DisordersScandinavian Journal of Clinical and Laboratory Investigation, 1972
- Proportional Release of Norepinephrine and Dopamine-β-Hydroxylase from Sympathetic NervesScience, 1971
- Serum Dopamine-Beta-Hydroxylase ActivityCirculation Research, 1971