MEDITERRANEAN TARGET-OVAL CELL SYNDROME IN AN ADULT CHINESE MALE: REPORT OF A CASE
- 1 February 1946
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 24 (2) , 259-261
- https://doi.org/10.7326/0003-4819-24-2-259
Abstract
Dameshek proposed the following criteria for the recognition of Mediterranean target-oval cell syndrome: The racial factor[long dash]ancestry stems from Mediterranean area; a reduction in Hb concn. in assocn. with a low color index; refractoriness to Fe therapy; the presence of increased numbers of target cells and reticulocytes in association with oval and stippled red corpuscles; the presence of increased hypotonic resistance of the erythrocytes; and the absence of such conditions as hepatic disease, steatorrhea, bleeding or Pb poisoning. A case of true Mediterranean target-oval cell syndrome is reported occurring in a soldier of pure Chinese ancestry who was born in China and came to this country at the age of 15 yrs. This is apparently the first reported case of this syndrome in an adult, full-blooded Chinese [male].Keywords
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