Quantifying Drug-Induced Changes in Parkinsonian Rigidity Using an Instrumental Measure of Activated Stiffness
- 1 February 1992
- journal article
- Published by Wolters Kluwer Health in Clinical Neuropharmacology
- Vol. 15 (1) , 1-12
- https://doi.org/10.1097/00002826-199202000-00001
Abstract
We review the literature on quantifying parkinsonian rigidity and present data from 124 subjects to demonstrate the clinical utility of activated stiffness to model rigidity. This method eliminates many of the confounding variables associated with the subjective assessment of rigidity. This 5-min computer-assisted procedure was highly reliable and sensitive to pharmacologic influences that produce and reduce parkinsonian rigidity.Keywords
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