Relationship of Technetium Tc 99m Sestamibi Scans to Histopathological Features of Hyperfunctioning Parathyroid Tissue

Abstract
Primary hyperparathyroidism is a common endocrinopathy reported to affect approximately 1 in 1000 individuals in their 50s, 60s, and 70s. Since the advent of preoperative imaging for the localization of pathologic parathyroid glands, management of primary hyperparathyroidism has evolved significantly. Currently, primary hyperparathyroidism is treated in many clinical settings by a minimally invasive approach instead of the more traditional bilateral neck exploration.