Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

This publication has 62 references indexed in Scilit:

• The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
  Nature Reviews Cancer, 2009
• Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy
  Published by Elsevier ,2008
• Activation of HIF‐1α in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway
  Journal of Cellular Physiology, 2008
• Regulation of TORC1 by Rag GTPases in nutrient response
  Nature Cell Biology, 2008
• Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34
  Cell Metabolism, 2008
• AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
  Published by Elsevier ,2008
• AKT/PKB Signaling: Navigating Downstream
  Cell, 2007
• mTOR and cancer: insights into a complex relationship
  Nature Reviews Cancer, 2006
• Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
  Oncogene, 2006
• mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
  Cell, 2002