Rod photoresponses in the absence of external sodium in retinae treated with phosphodiesterase inhibitors
- 1 December 1981
- journal article
- research article
- Published by Springer Nature in Experimental Brain Research
- Vol. 44 (4) , 427-430
- https://doi.org/10.1007/bf00238835
Abstract
Exposure of isolated toad retinae to phosphodiesterase inhibitors induced changes in the ionic permeability of rod cells. Under similar conditions intracellularly recorded light responses were observed also in the absence of external Na+. Hyperpolarizing photoresponses in Na+-free media required the presence of divalent cations among which Mg2+, Mn2+ and Ba2+ were the most effective.This publication has 18 references indexed in Scilit:
- The sodium current underlying the responses of toad rods to light.The Journal of Physiology, 1981
- Effect of ions on the light-sensitive current in retinal rodsNature, 1981
- Mechanism for selectively inhibiting the activation of cyclic nucleotide phosphodiesterase and adenylate cyclase by antipsychotic agents.1978
- Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins.The Journal of general physiology, 1977
- Electrical responses of rods in the retina of Bufo marinusThe Journal of Physiology, 1977
- Inhibitory and activators of cyclic nucleotide phosphodiesterase.1976
- Dark Ionic Flux and the Effects of Light in Isolated Rod Outer SegmentsThe Journal of general physiology, 1972
- Papaverine - induced inhibition of phosphodiesterase activity in various mammalian tissuesLife Sciences, 1971
- Electrical responses of single cones in the retina of the turtleThe Journal of Physiology, 1970
- Light-induced resistance changes in single photoreceptors ofnecturus andgekkoVision Research, 1969