COMPLETE SUBSIDENCE OF SCLERODERMA WITH DIHYDROTACHYSTEROL

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Abstract
This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. This case of diffuse scleroderma is being reported because of the remarkable, almost dramatic response to therapy with dihydrotachysterol; The patient has been observed and treated by us for the past five years. The clinical diagnosis of generalized scleroderma is usually not very difficult. The skin shows a boardlike thickening and appears to be stretched and hide bound. There is also a glistening with a characteristic ivory white sheen. Because of the extreme infiltration, the skin cannot be folded or picked up from the underlying connective tissues. The patient's face usually has a masklike appearance because of the tautness and increased density of the skin. Scleroderma runs a protracted and progressive course resulting in steadily increasing disability, restriction of motion and immobility. Ulcerations, especially of the finger tips, contractures and impairment of normal physiologic functions, such as deglutition, are not uncommon sequelae. The pathogenesis of diffuse generalized scleroderma is obscure.

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