Bioactive Sesquiterpenes from A Taiwanese Marine Sponge Parahigginsia sp.
- 19 March 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (4) , 573-576
- https://doi.org/10.1021/np980491p
Abstract
Five new sesquiterpenes, parahigginols A−D (1−4) and parahigginic acid (5), have been isolated from a Taiwanese marine sponge Parahigginsia sp. The structural assignments of the new compounds were based on their spectral data, including 1D and 2D NMR. Biological studies revealed that compounds 2−5 exhibited cytotoxicity against murine P-388 and human KB16, A549, and HT-29 tumor cells.Keywords
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