Low-Dose Thalidomide Therapy for Refractory Cutaneous Lesions of LupusErythematosus

Abstract
CUTANEOUS manifestations of lupus erythematosus (LE) are chronic, disfiguring lesions that may be associated with systemic disease. These cutaneous lesions can be simply classified into 3 categories of lesions: (1) vascular lesions seen in systemic lupus erythematosus (SLE); (2) interface lesions seen in chronic cutaneous lupus erythematosus (CCLE), subacute cutaneous lupus erythematosus (SCLE), or SLE; or (3) special lesions as seen in LE profundus or in vesiculobullous lesions.1 There is potential for overlap between CCLE and SCLE, between CCLE and LE profundus, and between CCLE/SCLE and SLE.2