Inhibition of Ribulose 1,5-Diphosphate Carboxylase by 6-Phosphogluconate
- 1 August 1972
- journal article
- Published by Oxford University Press (OUP) in Plant Physiology
- Vol. 50 (2) , 224-227
- https://doi.org/10.1104/pp.50.2.224
Abstract
6-Phosphogluconate is a much more effective inhibitor of the photosynthetic carboxylation enzyme, ribulose-1, 5-diphosphate carboxylase, than other sugar phosphates and sugar acids of the reductive and oxidative pentose phosphate cycles. The inhibition appears to be noncompetitive with ribulose 1,5-diphosphate. Since 6-phosphogluconate is unique to the oxidative cycle and inhibits at concentrations comparable to those found in vivo, it is proposed that its inhibition of the carboxylase may be a regulatory factor. If so, it would operate during darkness as a different control factor from those factors postulated to activate the carboxylase during photosynthesis.Keywords
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