Acute and latent leukopenic reaction to antipyrine
- 1 December 1980
- journal article
- research article
- Published by Springer Nature in Clinical Pharmacology & Therapeutics
- Vol. 28 (6) , 820-822
- https://doi.org/10.1038/clpt.1980.240
Abstract
During the past 10 yr, over 100 subjects received test doses of antipyrine [a pharmacological tool to assess the biotransformation capacity of the liver] for drug metabolism studies without any noticeable untoward effects. An immediate allergic reaction to antipyrine and a latent leukopenic reaction 8 wk later without any drug exposure is described. Leukoagglutination was demonstrated in vitro following the addition of antipyrine, aminopyrine, phenylbutazone or sulfinpyrazone to blood taken from the subject.This publication has 1 reference indexed in Scilit:
- Agranulocytosis due to the Occurrence of Leukocyte-AgglutininsActa Haematologica, 1952