Effects of amiloride and W-7 on the chemoreception of NaCl and KCl in the blowfly: implications for the salt quality
- 28 September 2000
- journal article
- Published by Brill in Sensory Neuron
- Vol. 3 (2) , 119-125
- https://doi.org/10.1163/156856500744784
Abstract
The role of amiloride in the labellar responses to various salt stimuli in the blowfly Protophormia terraenovae was studied with the aim of ascertaining whether salt reception is mediated by an amiloride-sensitive cation conductance. Results indicate that, unlike the case of NaCl, KCl sensitivity is inhibited by amiloride. W-7 (a calmodulin antagonist, involved in the Ca2+ cascade) strongly inhibits the chemosensillar response to both NaCl and KCl. Implications of transduction mechanisms for the 'salt' and 'water' chemoreceptors are discussedKeywords
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