Brain metastasis development and poor survival associated with carcinoembryonic antigen (CEA) level in advanced non-small cell lung cancer: a prospective analysis
Open Access
- 22 April 2009
- journal article
- Published by Springer Nature in BMC Cancer
- Vol. 9 (1) , 119
- https://doi.org/10.1186/1471-2407-9-119
Abstract
Central nervous system is a common site of metastasis in NSCLC and confers worse prognosis and quality of life. The aim of this prospective study was to evaluate the prognostic significance of clinical-pathological factors (CPF), serum CEA levels, and EGFR and HER2 tissue-expression in brain metastasis (BM) and overall survival (OS) in patients with advanced NSCLC.Keywords
This publication has 54 references indexed in Scilit:
- Cancer Statistics, 2008CA: A Cancer Journal for Clinicians, 2008
- Gender differences in non-small cell lung cancer: A population-based studyEuropean Journal of Surgical Oncology, 2007
- Her2-Targeted Therapies in Non–Small Cell Lung CancerClinical Cancer Research, 2006
- Association of HER‐2 overexpression with prognosis in nonsmall cell lung carcinoma: A metaanalysisCancer, 2005
- The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissuesSeminars in Cancer Biology, 1999
- Recursive partitioning analysis (RPA) of prognostic factors in three radiation therapy oncology group (RTOG) brain metastases trialsPublished by Elsevier ,1997
- Treatment of single brain metastasis: Radiotherapy alone or combined with neurosurgeryAnnals of Neurology, 1993
- A Randomized Trial of Surgery in the Treatment of Single Metastases to the BrainNew England Journal of Medicine, 1990
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987
- Preoperative carcinoembryonic antigen and survival after resection of lung cancerRespiratory Medicine, 1980