Peripheral nerve—spinal cord anastomosis for experimental cord transection

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Abstract
Complete lesions were made in the spinal cord of dogs by removing a portion of the spinal cord and its ensheathing meninges. One to 2 months later, the distal stump of an intercostal nerve having its origin above the lesion was inserted into the isolated distal segment of the spinal cord. The dogs became capable of longer periods of standing and more coordinated walking in the following months. Five animals which had developed reflex walking and standing lost these functions after surgical section of the inserted nerve. Histologically, nerve fibers and Schwann-like cells extended from the distal end of the inserted peripheral nerve into the isolated distal segment of the spinal cord.

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