Stimulation of Acyl-CoA: Cholesterol Acyltransferase Activity by Hyperlipemic Serum Lipoproteins
- 1 September 1977
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 155 (4) , 501-506
- https://doi.org/10.3181/00379727-155-39838
Abstract
Cholesteryl ester synthesis by the microsomal fraction from rat hepatoma cells was stimulated by preincubation of the microsomal fraction with lipoproteins obtained from hyperlipemic rabbit sera. Lipoproteins from normolipemic sera had no stimulatory effect. Growth of cells in hyperlipemic rabbit sera also increased microsomal cholesteryl ester synthesis. Increased cholesteryl ester synthesis was accompanied by an increased microsomal-free cholesterol content.This publication has 4 references indexed in Scilit:
- Production of cholesteryl ester-rich, anisotropic inclusions by mammalian cells in cultureExperimental and Molecular Pathology, 1977
- Cellular cholesterol ester accumulation induced by free cholesterol-rich lipid dispersions.Proceedings of the National Academy of Sciences, 1976
- STUDIES ON MECHANISM OF FATTY ACID SYNTHESIS .19. PREPARATION AND GENERAL PROPERTIES OF PALMITYL THIOESTERASE1968
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951