Tolerance of Fungi to Organic Fungicides

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Abstract
Tolerance to organic fungicides used in the control of fungal diseases of plants or storage rots has created practical difficulties in only a few instances. Resistance can develop easily to some categories of toxicants and may become of importance in the field. There is no evidence that nongenetic adaptation to fungicides, if at all possible, can be of practical importance, and attention should be concentrated on genetically well-defined resistance. Such studies should utilize the mutation-induction techniques which, particularly with filamentous fungi, may prove much more successful than "training" on gradually higher concentrations of the fungicide. Which fungus to choose may be of considerable importance in this respect. It seems that fungi exhibiting considerable resistance in the wild type are unsuitable, and attempts to induce tolerance should use more sensitive species.

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