Lesion Patterns and Mechanism of Ischemia in Internal Carotid Artery Disease
Open Access
- 1 October 2002
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 59 (10) , 1577-1582
- https://doi.org/10.1001/archneur.59.10.1577
Abstract
THE CLINICAL syndromes from extracranial internal carotid artery (ICA) occlusive disease result from 2 basic mechanisms—from embolism and from low flow due to inadequate collateral circulation distal to a hemodynamically significant stenosis or occlusion.1 Concurrently, regarding the topography of the ischemic stroke lesion in extracranial ICA disease, territorial and border-zone infarctions are the 2 major patterns. Although hemodynamic compromise due to low flow in the border-zone areas has usually been postulated to explain the infarcts in these regions,2,3 the actual cause of border-zone infarction is still controversial.Keywords
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