In Vitro Cutaneous and Percutaneous Delivery and in Vivo Efficacy of Tetracaine from Liposomal and Conventional Vehicles
- 1 January 1994
- journal article
- clinical trial
- Published by Springer Nature in Pharmaceutical Research
- Vol. 11 (11) , 1593-1598
- https://doi.org/10.1023/a:1018909821048
Abstract
The aim of this study was to quantitate drug delivery and correlate drug concentration in the skin with anesthetic effect. The rate of delivery of radiolabelled tetracaine from two different liposome...Keywords
This publication has 10 references indexed in Scilit:
- Noninvasive Percutaneous Induction of Topical Analgesia by a New Type of Drug Carrier, and Prolongation of Local Pain Insensitivity by Anesthetic LiposomesAnesthesia & Analgesia, 1992
- Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration forceBiochimica et Biophysica Acta (BBA) - Biomembranes, 1992
- Thickly and Thinly Applied Lignocaine-Prilocaine Cream Prior to Venepuncture in ChildrenAnaesthesia and Intensive Care, 1991
- Topical liposomal tetracaine for i.v. cannulation.1990
- IN VIVO ASSESSMENT OF PERCUTANEOUS LOCAL ANAESTHETIC PREPARATIONSBritish Journal of Anaesthesia, 1989
- CONCENTRATION-RESPONSE ANALYSIS OF PERCUTANEOUS LOCAL ANAESTHETIC FORMULATIONSBritish Journal of Anaesthesia, 1988
- A Device for Uniform Testing of Sensory Neural Blockade during Regional AnesthesiaAnesthesia & Analgesia, 1987
- CLINICAL STUDY OF A LIGNOCAINE-PRILOCAINE CREAM TO RELIEVE THE PAIN OF VENEPUNCTUREBritish Journal of Anaesthesia, 1985
- Methods for In Vitro Percutaneous Absorption Studies IV: the Flow-Through Diffusion CellJournal of Pharmaceutical Sciences, 1985
- The efficacy of local anesthetics in blocking the sensations of itch, burning, and pain in normal and “sunburned” skinClinical Pharmacology & Therapeutics, 1971