ChemInform Abstract: A Search for Calcium-Channel Activators in the Verapamil Series.
- 26 December 1989
- journal article
- research article
- Published by Wiley in ChemInform
- Vol. 20 (52) , 449-464
- https://doi.org/10.1002/chin.198952109
Abstract
Reaction of the nitriles (I) with 1-bromo-3-chloropropane (II) yields the δ-cyano chlorides (III) which are coupled with the amine (IV), producing the verapamil analogues (V).Keywords
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