Is prolonged antibiotic prophylaxis after major surgery associated with an increased risk of nosocomial bloodstream infection?
- 1 April 2000
- journal article
- other
- Published by Wolters Kluwer Health in Journal of the American College of Surgeons
- Vol. 190 (4) , 503-504
- https://doi.org/10.1016/s1072-7515(00)00218-0
Abstract
We read with great interest the study by Namias and associates, 1 Namias N. Harvill S. Ball S. et al. Cost and morbidity associated with antibiotic prophylaxis in the ICU. J Am Coll Surg. 1999; 188 : 225-230 Abstract Full Text Full Text PDF PubMed Scopus (53) Google Scholar suggesting that the common practice of extending antibiotic prophylaxis (ABP) after major surgery is associated with a significantly increased risk of nosocomial bloodstream infection (BSI). The authors observed 6 cases of BSI among 180 patients receiving short ABP, compared with 16 BSI cases in 94 patients with extended ABP (crude odds ratio 5.9, 95% confidence interval [CI 95] 2.1 to 17.8, p < 0.001).This publication has 2 references indexed in Scilit:
- Cost and morbidity associated with antibiotic prophylaxis in the ICUJournal of the American College of Surgeons, 1999
- CDC definitions for nosocomial infections, 1988American Journal of Infection Control, 1988