Simple (Imidazol-2-ylidene)-Pd-Acetate Complexes as Effective Precatalysts for Sterically Hindered Suzuki−Miyaura Couplings
- 26 March 2005
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 7 (9) , 1829-1832
- https://doi.org/10.1021/ol050472o
Abstract
[reaction: see text] A simplified synthesis of N-heterocyclic carbene (NHC)Pd-carboxylate complexes and their activity in Suzuki-Miyaura cross-coupling reactions are described. Coupling of sterically hindered aryl and activated alkyl chlorides bearing beta-hydrogens has been successfully achieved.Keywords
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