Alterations in chemical composition of canine heart after sympathetic denervation

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Abstract
Sympathetic denervation of the canine heart, which is extensive enough to insure depletion of myocardial catecholamines, results in an increased accumulation of myocardial fat and carbohydrate substances. Myocardial histamine, ubiquinone and nitrogen contents are unaffected. These observations provide additional evidence for the participation of the autonomic nervous system in the regulation of cardiac metabolism.