Malignant Argentaffinoma Associated with Cardiovascular Abnormalities

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Abstract
THERE has recently been considerable interest in the association of argentaffin tumors with valvular lesions of the heart.1 2 3 4 5 The unusual character of this association was first recognized by Biorck, Axen and Thorson,1 although they were able to find a few cases previously reported. In general these patients all had argentaffin tumors, which had often extensively metastasized to the liver. However, in a case reported by Arnett and Long6 the tumor was thought to be a carcinoma of the pancreas, and in 1 of the cases of Rosenbaum et al.,7 the neoplasm was interpreted as a bile-duct carcinoma. The cardiac component . . .