Biosynthesis of aspyrone, a metabolite of Aspergillus melleus: advanced precursor studies to identify the product of the polyketide synthase
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 16,p. 1108-1110
- https://doi.org/10.1039/c39910001108
Abstract
Incorporation studies with deuterium-labelled compounds, using 2H NMR spectroscopy as method of analysis, have shown that a C10 acid, (4E,6E,8E)-3-hydroxydeca-4,6,8-trienoic acid, is incorporated intact into aspyrone when administered to growing cells of Aspergillus melleus.Keywords
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