WORKSHOP ON ASSESSMENT OF RESPIRATORY CONTROL IN HUMANS .1. METHODS OF MEASUREMENT OF VENTILATORY RESPONSES TO HYPOXIA AND HYPERCAPNIA

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Abstract
Because abnormalities in the chemical regulation of ventilation may occur in the absence of lung disease [human] and still produce hypoxia and hypercapnia, some standardization in methods and terminology was proposed. Quantification of the stimulus/response relationship to hypercapnia may be accomplished by steady state and rebreathing methods. The effect of lung disease on the usefulness of ventilation as a measure of chemoreceptor output is discussed, along with procedures recommended for evaluating sensitivity to hypoxia and hypercapnia.

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