Allosteric effects of DNA on transcriptional regulators
- 1 April 1998
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 392 (6679) , 885-888
- https://doi.org/10.1038/31860
Abstract
Selective gene transcription is mediated in part by regulatory proteins that bind to DNA response elements. These regulatory proteins receive global information from signal-transduction events. But transcriptional regulators may also be modified in an allosteric manner by response elements themselves to generate the pattern of regulation that is appropriate to an individual gene.Keywords
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