Magnetic Resonance Imaging of the Brain in Patients with Anosmia and Hypothalamic Hypogonadism (Kallmann's Syndrome)*

Abstract
Kallmann''s syndrome is characterized by hypogonadotropic hypogonadism and anosmia. Postmorten studies have revealed either hypoplasia or aplasia of the rhinencephalon, respectively, in patients with hyposmia and anosmia. This anatomical defect has now been demonstrated in vivo in four patients with Kallmann''s syndrome by magnetic resonance imaging.