Thienamycin: New Beta-Lactam Antibiotic with Potent Broad-Spectrum Activity
Open Access
- 1 April 1979
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 15 (4) , 518-521
- https://doi.org/10.1128/aac.15.4.518
Abstract
Thienamycin, a new beta-lactam antibiotic, exhibited potent, broad-spectrum activity in vitro against gram-negative bacilli and gram-positive cocci, including many isolates resistant to currently available antibiotics. All isolates were inhibited at concentrations less than or equal to 25 μg/ml, with the exception of 12% of isolates of Enterobacter spp. and 3% of isolates of Serratia marcescens. Its activity decreased with an increase in inoculum concentration of from 105 to 107 cells per ml.This publication has 5 references indexed in Scilit:
- In Vitro Activity of ThienamycinAntimicrobial Agents and Chemotherapy, 1978
- Piperacillin: In Vitro EvaluationAntimicrobial Agents and Chemotherapy, 1978
- PC-904, a New Semisynthetic PenicillinAntimicrobial Agents and Chemotherapy, 1978
- Azlocillin: In Vitro Studies of a New Semisynthetic PenicillinAntimicrobial Agents and Chemotherapy, 1977
- Mezlocillin: In Vitro Studies of a New Broad-Spectrum PenicillinAntimicrobial Agents and Chemotherapy, 1977