RENAL OSTEODYSTROPHY

Publisher Website
Google Scholar
Abstract
Renal osteodystrophy is a complex of skeletal responses to renal disease, which includes : (1) osteomalacia (adults) and rickets (children); (2) osteitis fibrosa; and (3) osteosclerosis. The latter may be the result of treatment. Soft tissue calcifications occur in long-standing disease. Renal osteodystrophy may be divided into acquired or glomerular form (due most often to chronic pyelonephritis), and the congenital or tubular form, e.g., vitamin D resistant rickets, Fanconi syndrome, and renal tubular acidosis. Impaired intestinal absorption of calcium and phosphorus may be a common link between the two forms. Roentgenographically, renal and dietary rickets differ only in severity. The greater degree of change in renal rickets may be related to age of onset and body weight. Osteomalacia is diffuse, or localized (pseudofractures). Osteitis fibrosa occurs most characteristically as subperiosteal bone resorption. Osteosclerosis is most common in the thoracolumbar spine at the superior and inferior vertebral borders. Soft tissue, arterial, and renal parenchymal calcifications occur late. The disease will become more prevalent with increasing use of long-term dialysis.

This publication has 0 references indexed in Scilit: