DIFFERENCE IN THE ACTIVATING EFFECT OF NORMAL AND HYPERTENSIVE PLASMA ON INTESTINAL SEGMENTS TREATED WITH RENIN

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Abstract
Heparinized plasma derived from blood of some patients with essential hypertension causes greater renin-activation than does normal human blood. Plasma from dogs with exptl. hypertension also exhibits this heightened power compared with plasma of normal dogs. The humoral mechanism in the 2 types of hypertension apparently have much in common and hypertensive patients either have increased amts. of renin-activator in the blood, or decreased amts. of renin-inhibitor, or both.

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