Moxalactam Concentration in Human Aqueous Humor After Intravenous Administration
- 1 August 1982
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 100 (8) , 1334-1336
- https://doi.org/10.1001/archopht.1982.01030040312024
Abstract
• Two grams of moxalactam disodium was administered intravenously to 20 patients before cataract extraction. Mean aqueous humor concentrations of moxalactam were 0.92, 0.87, 1.98, 2.13, and 1.24 μg/mL 30 minutes and 1, 2, 4, and 6 hours, respectively, after treatment. Adequate levels against Staphylococcus aureus and Staphylococcus epidermidis were not achieved. With the exception of Pseudomonas species, therapeutic levels three to ten times greater than the median minimum inhibitory concentration of moxalactam against Enterobacteriaceae were achieved for up to six hours after administration.This publication has 15 references indexed in Scilit:
- Cephradine Levels in Human Aqueous HumorArchives of Ophthalmology (1950), 1981
- Cefoxitin Levels in Human Aqueous HumorAmerican Journal of Ophthalmology, 1980
- INTERACTION BETWEEN MOXALACTAM AND ALCOHOLThe Lancet, 1980
- Cefaclor Levels in Human Aqueous HumorArchives of Ophthalmology (1950), 1980
- In Vitro Activity of LY127935Antimicrobial Agents and Chemotherapy, 1979
- Etiology and Diagnosis of Bacterial Postoperative EndophthalmitisOphthalmology, 1978
- Prevention of Postoperative EndophthalmitisOphthalmology, 1978
- Cefamandole Levels in Primary Aqueous Humor in ManAmerican Journal of Ophthalmology, 1978
- Further Observations on the Diagnosis, Cause, and Treatment of EndophthalmitisAmerican Journal of Ophthalmology, 1976
- Penetration of Antistaphylococcal Antibiotics Into the Human EyeAmerican Journal of Ophthalmology, 1974