Clinical Evaluation of a new Anthelmintic—Thiabendazole [2-(4′-Thiazolyl)-Benzimidazole]
- 1 May 1964
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 13 (3) , 412-416
- https://doi.org/10.4269/ajtmh.1964.13.412
Abstract
Summary Thiabendazole administered to 61 patients with intestinal helminthiasis in single doses of 1.25 or 2.5 grams was found to be effective in Ascaris lumbricoides infection in a dose of 1.25 g. Its action against Ancylostoma duodenale was comparable in effectiveness to 2 g of bephenium or 3 ml of tetrachlorethylene, on the basis of mean percentage reduction in egg-count. It had no marked effect on Trichuris trichiura infection. In a dose of 2.5 g it produced giddiness and vomiting.Keywords
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