Involvement of P1 Adhesin in Gliding Motility of Mycoplasma pneumoniae as Revealed by the Inhibitory Effects of Antibody under Optimized Gliding Conditions
Open Access
- 1 March 2005
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 187 (5) , 1875-1877
- https://doi.org/10.1128/jb.187.5.1875-1877.2005
Abstract
To examine the participation of P1 adhesin in gliding of Mycoplasma pneumoniae , we examined the effects of an anti-P1 monoclonal antibody on individual gliding mycoplasmas. The antibody reduced the gliding speed and removed the gliding cells from the glass over time in a concentration-dependent manner but had only a slight effect on nongliding cells, suggesting that the conformational changes of P1 adhesin and its displacement are involved in the gliding mechanism.Keywords
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